Prof. Dr. Pedro Beltrao

Area of Research

Description of Research Interest

Discovering how genetic variation leads to changes in traits underlies the study of human disease and the understanding of the evolutionary process. What makes each human individual different and the diversity of life on earth are, to some extent, determined by differences in DNA. How these DNA differences manifest in a variety of shapes, capabilities and even different propensity to disease remains a mystery. Our long term goal is to have comprehensive models of how DNA changes result in differences in biomolecules, their interactions and ultimately different traits or disease.

Special Expertise

• Studies of cell-type and tissue specific protein-protein interactions
  
• Protein network-based studies of human genetics data
  
• Impact of of protein variants on protein structure and function
  
• Computational methods focused on mechanisms linking genotype to phenotype