Prof. Dr. med. Matthias Guckenberger

Area of Research

Description of Research Interest

Matthias Guckenberger is the Chairman of the Department for Radiation Oncology, University Hospital Zurich (USZ). Development, translation and clinical evaluation of advanced imaging and radiotherapy planning and delivery technologies into cancer treatment is his major research focus. Research is clinically focused on early and locally advanced stage lung cancer, prostate cancer and in particular oligo-metastatic disease. Recent projects established Radiomics, a methodology using advanced mathematical quantification of radiological images, as a potential prognostic and predictive biomarker. Mathematical modelling of tumor and normal tissue response to radiotherapy was extended for the use of advanced statistical methodologies such as support-vector machine learning and cure rate models. Retrospective register studies as well as prospective clinical trials have been conducted for evaluation of advanced radiotherapy technologies.

Special Expertise

Radiomics
Outcome Modelling
Lung Cancer
Oligo-metastasis

Shareable Platforms, Services, Equipment & Infrastructure

Radiomics
Small animal high precision radiotherapy