Prof. Dr. med. Markus Stoffel

Area of Research

Description of Research Interest

Stoffel's major research interests focus on molecular mechanisms regulating glucose and lipid homeostasis, insulin secretion and insulin signaling and controlling of gene regulatory networks through transcription factors and small non-coding RNAs. His major contributions have been the identification and characterization of genes responsible for genetic forms of early-onset type 2 diabetes, the identification of growth-promoting genes and networks in pancreatic b-cells, the characterization of transcriptional networks responsible for the molecular switches between fasting and postprandial metabolism and the discovery and characterization of microRNAs in the control of pancreatic beta cell growth and metabolism.

Special Expertise

Islet biology
Metabolism
Gene editing
miRNA biology
RNA therapeutics

Shareable Platforms, Services, Equipment & Infrastructure

NEXUS
Pancreatic islet perfusion
Liver perfusion
Gene editing

Member of Collaborative/interdisciplinary Research Consortia

NCCR RNA Biology and Disease