Prof. Dr. med. Johannes Loffing

Area of Research

Description of Research Interest

The general goal of our research is to understand how the kidneys maintain ion balance and how deranged underlying mechanism lead to human diseases including arterial hypertension. Current projects focus on the identification and characterization of novel candidate genes that control glomerular filtration, adaptive renal cell growth and epithelial sodium transport. Moreover, we elucidate regulatory mechanisms by which the kidney and other organs cooperate to control potassium homeostasis and blood pressure.

Special Expertise

Kidney histology (LM and EM)

Shareable Platforms, Services, Equipment & Infrastructure

Large-scale isolation of renal tubules
Ex vivo kidney slice culture / experiments
Rodent tail-cuff blood pressure recordings