Prof. Dr. Federica Sallusto

Area of Research

Description of Research Interest

We study the human system to address fundamental questions in the context of the immune response to different classes of antigens, such as microbial pathogens, allergens or self-antigens, to gain insights into mechanisms that induce host protection or immune-mediated pathology. We are conducting studies to understand why in patients with chronic or disseminated infections, including patients with rare primary immunodeficiencies caused by genetic disorders, the immune system fails to protect the host. We also perform studies to understand how some individuals mount immune responses against not harmful environmental antigens or self-antigens, which cause allergy and autoimmunity. In this context, we are conducting studies in patients suffering from neurological disorders, including multiple sclerosis and narcolepsy, in collaboration with clinicians at university and cantonal hospitals in Zurich, Bern, Lugano and Genoa. Finally, we are developing new tools to advance the highly active and exciting field of cancer immunotherapy.

Special Expertise

Human immunology
Cell cultures
Human T and B lymphocyte biology
Human dendritic cell biology

Shareable Platforms, Services, Equipment & Infrastructure

HT cell based screenings