Prof. Didier Surdez

Area of Research

Epigenetics Genetics Molecular Biology Musculoskeletal Sciences Oncology Pediatrics Personalized Medicine Proteomics/Transcriptomics, ...-omics

Description of Research Interest

Didier Surdez is an expert in solid pediatric cancer research, with a particular focus on Ewing sarcoma. His research focuses on the regulation, dynamics and functional dependencies of key oncogenes and tumor suppressors in these pediatric sarcomas. To investigate these mechanisms, the Surdez lab develops advanced preclinical models, including patient-derived models, isogenic cellular systems, and functional screening methods. Through this integrative approach, the Surdez lab aims to translate fundamental discoveries into innovative therapeutic strategies for pediatric and bone cancers.

Special Expertise

Bone and soft tissue sarcoma
pediatric oncology
preclinical models (Tumoroids, PDX, 3D spheroids...)
Epigenetics and 3D chromatin organisation
real-time oncogene and chromatin dynamics

Shareable Platforms, Services, Equipment & Infrastructure

Drug response profiling in sarcoma

Member of Collaborative/interdisciplinary Research Consortia

Zurich Precision Oncology for Children (ZPOC): A connected platform to accelerate pediatric precision oncology care (UMZH Technology Initiatives)

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Prof. Didier Surdez

University of Zurich Faculty of Medicine

University Hospital Zurich

University Children's Hospital Zurich

Balgrist University Hospital

Deprtment of Orhtopedics

didier.surdez@uzh.ch www.usz.ch