Prof. Dr. Christoph Messner
Area of Research
Description of Research Interest
Proteins are the functional units of cells and are essential for all biological processes. This is why they play a central role in disease—and why measuring them is so important: proteins are the targets of most drugs, are highly informative for diagnosis, and are key enablers of personalised medicine approaches.Our team has deep expertise in mass spectrometry–based proteomics, with a strong track record in developing high-throughput workflows. With novel technologies now available, we can analyse large patient cohorts at scale while also profiling rare cell populations that were previously inaccessible and often obscured in bulk measurements. Our goal is to uncover molecular mechanisms and biomarkers in immunology and oncology, accelerate the clinical translation of proteomic insights into novel therapies and diagnostics, and ultimately improve patient care.
Special Expertise
- Proteomics (LC–MS/MS) for discovery and targeted protein quantification
- Large-cohort proteomics across diverse sample matrices (cells, tissues—FFPE and fresh-frozen, plasma/serum)
- Low-input / rare-sample proteomics for sorted immune cell populations (including very small cell numbers) and limited clinical material
- Targeted metabolomics
- (Prote)omics data analysis and statistics
- Machine learning / predictive modelling on (prote)omics datasets
Shareable Platforms, Services, Equipment & Infrastructure
- Mass spectrometry platforms for targeted and discovery workflows
- Computational infrastructure and analysis pipelines
